The Mitochondrial ToxGlo™ Assay measures ATP and membrane integrity biomarker surrogates to identify mitochondrial dysfunction in a fast, easy to automate, "add-mix-read" format.
Mitochondrial ToxGlo™ Assay
A cell-based multiplexed method that measures ATP as an indicator of mitochondrial function and uses a membrane integrity biomarker to distinguish primary mitochondrial dysfunction from secondary cytotoxic events.
Here we demonstrate a method to assess and triage potential mitochondrial toxicities from large chemical libraries or medicinal modification efforts.
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